How to cite TrialCurve

Updated 2026-09-25 · TrialCurve methods team

Citation

TrialCurve (2026). Automated reconstruction of individual patient data from published
Kaplan–Meier figures [software], version 0.1.0. https://trialcurve.com

Guyot P, Ades AE, Ouwens MJNM, Welton NJ. Enhanced secondary analysis of survival data:
reconstructing the data from published Kaplan-Meier survival curves.
BMC Med Res Methodol. 2012;12:9. doi:10.1186/1471-2288-12-9

BibTeX

@software{trialcurve2026,
  title   = {TrialCurve: automated reconstruction of individual patient data from published Kaplan-Meier figures},
  year    = {2026},
  version = {0.1.0},
  url     = {https://trialcurve.com}
}
@article{guyot2012,
  author  = {Guyot, Patricia and Ades, A. E. and Ouwens, Mario J. N. M. and Welton, Nicky J.},
  title   = {Enhanced secondary analysis of survival data: reconstructing the data from published Kaplan-Meier survival curves},
  journal = {BMC Medical Research Methodology}, year = {2012}, volume = {12}, pages = {9},
  doi     = {10.1186/1471-2288-12-9}
}

Methods paragraph template

Every API result includes a filled-in version of this paragraph (validation.methods_paragraph):

Kaplan–Meier curves for [endpoint] were digitised from [publication, figure] using TrialCurve
(version 0.1.0), which reads axis labels and the numbers-at-risk table and measures each curve
by image analysis. Individual patient data were reconstructed with the algorithm of Guyot et
al. (2012). Reconstruction was validated against the published hazard ratio ([value]) and median
survival ([values]); reconstructed values were [values]. A second independent extraction agreed
within [tolerance].

AI-use disclosure (EU JCA and other HTA bodies)

For dossiers that follow the HTA Coordination Group's AI principles, use the ai_use_disclosure.suggested_statement field. It names the tool, version, date, model and provider, and states that a human analyst reviewed the output. See reconstructed IPD in HTA.